Kitano Medical Research Institute, Public Interest Incorporated Foundation, Tatsunokofukai

In rheumatoid arthritis, inflammatory molecules such as TNF-α and IL-6, and immune cells called T cells, play an important role in bone destruction.
In recent years, drugs (known as biologics) that can pinpoint and suppress these molecules and cells have been developed and are attracting attention.
Currently, there are five biologics available: Remicade, Humira, Enbrel, Actemra, and Orencia. They are used when symptoms cannot be controlled with regular anti-rheumatic drugs, and have an excellent efficacy rate of 80-90%.
It has also been suggested that early use may allow for future discontinuation of treatment.
However, it can also weaken the immune system and increase the risk of developing infections.
Before using these biologics, please consult a specialist first.