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Research Institute

Research Department Introduction

Research Institute

Medical Research Institute

Research Department Introduction

FY2021 Research Department Organization Table

We transitioned to a new research department in April 2021.

Director of Medical Research Institute
  • TAKETO(Taketo) Makoto
Deputy Director, Medical Research Institute
  • FUKUI Motonari (Vice Director and Chief of the Department of Respiratory Medicine)
  • MUKAIHideyuki (Chief of Clinical Laboratory Department)
New research department name About the New Research Department Main department New Research Director
tumor The Oncology Division conducts research into malignant tumors of the digestive system, respiratory system, genitourinary system, female reproductive system, breast, and hematopoietic system. In clinical practice, we conduct research based on scientific evidence, not just guidelines, and we also engage in basic research using molecular biology and applied research in clinical settings, with the aim of further improving cancer treatment.
  • Gastrointestinal surgery
  • Gastroenterology
  • respiratory surgery
  • breast surgery
  • Urology
  • Obstetrics and Gynecology
  • Hematology
  • Medical Oncology
  • Pathology
  • Palliative Care
 HONJO Gen
(pathology)
Breathing/Circulation The Department of Respiratory and Circulatory Systems conducts research into diseases of the heart, blood vessels, and lungs, which are responsible for the respiratory and circulatory systems essential for maintaining life, as well as the physiological functions and disorders of the respiratory and circulatory systems.We also conduct research into medical devices necessary for maintaining life in the event of respiratory and circulatory disorders.
  • Cardiology
  • Cardiac Arrhythmia
  • Cardiovascular Surgery
  • Respiratory internal medicine
  • Department of Clinical Engineering
 HARUNA Tetsuya
(arrhythmia)
Endocrinology, metabolism, and kidneys The Department of Endocrinology, Metabolism and Nephrology conducts basic and clinical research aimed at elucidating the pathology of metabolic diseases such as diabetes and various endocrine diseases, as well as personalized medicine.In addition to clinical research utilizing kidney disease and kidney biopsy databases and basic research on glomerular diseases, we also conduct research on nutrition and dietary approaches to improve the pathology and treatment progress of various diseases.
  • Diabetic endocrinology
  • Nephrology
  • Nutrition Department
 HAMASAKI Akihiro
(in sugar)
Inflammation/immunity Inflammation is a biological response to injury, and is also triggered by the immune system, which is a mechanism that primarily eliminates pathogens and foreign substances. The Division of Inflammation and Immunology studies innate and adaptive immunity to self and non-self antigens, as well as their associated inflammatory responses, with the aim of elucidating the pathology of infectious diseases and immune disorders and establishing methods for their treatment and prevention.
  • Rheumatology and Collagen Diseases
  • dermatology
  • Infectious disease department
 IMURA Yoshitaka
(Rheumatism)
Nerves and sensory-motor organs The Department of Neurology and Sensorimotor Systems is researching pathologies that occur in the system that integrates and interprets information from the outside world, including visual, auditory, superficial, and proprioceptive senses, in the brain, and connects it to voluntary movement of muscles, bones, and joints via the central and peripheral nervous system. For example, after many years of research, regenerative therapy for the eardrum has been approved as a medical treatment covered by health insurance. We are also researching regenerative medicine for spinal cord injuries.
  • Neurology
  • ophthalmology
  • Neuropsychiatry
  • orthopedic surgery
  • plastic surgery
  • Neurosurgery
  • Otolaryngology/Head and Neck Surgery
 TODA Hiroki
(neuropathic)
Development and regeneration The Department of Development and Regeneration conducts clinical research in various specialized fields, such as immunology and allergy, hematology, neurology, metabolism and endocrinology, and neonates and premature infants in the fields of pediatrics and pediatric surgery. We publish case reports and clinical research results that lead to pathological elucidation and treatment, and at the same time, we work in cooperation with Kyoto University to focus on training research physicians.
  • Pediatrics
  • Pediatric Surgery
 SHIOTA Mitsutaka
(Children)
Pathophysiology and Pharmacology The Department of Pathophysiology and Pharmacology conducts research into the pathophysiology of the body's invasive response in acute severe illnesses such as surgery and sepsis in the Department of Anesthesiology, Intensive Care Unit, and Emergency Department, as well as the pharmacology that controls it. In addition, the Department of Pharmacy conducts clinical research aimed at improving the efficacy and safety of drug therapy.
  • Anesthesiology
  • intensive care department
  • Emergency Department
  • Pharmacy Department
 ONOUE Masahide
(drugs)
Health/health The Health and Wellness Department primarily conducts its own research on disease prevention and health promotion, as well as collaborative research with other research departments. Research is focused on tumors and the body's response to radiation, the safety of medical equipment and drugs, and lifestyle habits and disease prevention methods. In addition to the safety of testing and blood transfusions, the department also conducts research on medical information management and data mining, clinical research aimed at improving the quality of nursing, research aimed at improving physical function through rehabilitation, and research into the occurrence and prevention of oral diseases.
  • Radiology Department
  • Health Management Center
  • Clinical Laboratory Department
  • Medical Information Department
  • Nursing Department
  • Rehabilitation Department
  • Dentistry and Oral Surgery
 TERAI Mineko
(nursing)

Public research funding adoption and management status

2025（令和7）年8月現在

Grant-in-Aid for Scientific Research (Principal Investigator)

Event Research representative Research topic 　
Grant-in-Aid for Scientific Research (C) 松原雄 免疫チェックポイント阻害薬に関連した腎障害における三次リンパ節の機能解析 　
Grant-in-Aid for Scientific Research (C) 大角明宏 ドナー肺の好中球細胞外トラップを標的とした新規移植前治療法の開発 　
Grant-in-Aid for Scientific Research (C) 中嶋綾 喉頭癌・下咽頭癌の放射線治療における喉頭機能温存予測モデルの開発 　
Grant-in-Aid for Scientific Research (C) 宮部結城 放射線治療において椎体の屈曲・伸展・回旋による誤差を検出補正する方法の検討 　
Grant-in-Aid for Scientific Research (C) 稲垣暢也 GIP/GLP-1受容体共刺激による血糖降下・体重減少作用増強メカニズムの解明 　
Grant-in-Aid for Scientific Research (C) 戸田弘紀 パーキンソン病・本態性振戦患者における小脳・視床・皮質回路の機能解剖の解明 　
Grant-in-Aid for Scientific Research (C) 堀江昭史 ヒト末梢血単核球(PBMC)の免疫寛容変化による胚着床改善効果の機能解明 　
Grant-in-Aid for Scientific Research (C) 原田博之 マルチオミクス解析による若年性舌癌の発症機構の解明 New
Grant-in-Aid for Scientific Research (C) Masaru Takahashi USAG-1を標的分子とした分子標的治療による歯の再生 New
Grant-in-Aid for Scientific Research (C) 榊原敦子 がん対策推進と患者の意思決定支援を目的とする「子宮頸がん予後予測モデルの開発」 新規　
Young Researchers 前川久継 大腸癌患者由来癌細胞ライブラリーを用いた癌幹細胞性の可塑性に関する研究 　
Young Researchers 渋江公尊 膵α細胞のIRS1制御性オートファジーにて調節されるグルカゴン分泌調節機構の探索 　
Young Researchers 山本健人 大腸癌におけるFGFR遺伝子が新規分子標的治療薬の感受性にもたらす影響と臨床的意義 　
Young Researchers 川添准矢 ヒスタミン受容体シグナル制御による肝虚血再灌流障害の制御および肝移植への応用 　
Support for starting research activities 石村拓也 機械学習を用いた腹膜透析継続可能期間予測モデルの開発 New

Grants-in-Aid for Scientific Research (shared)

Event Co-researcher Research topic  
基盤研究(A) 堀江昭史 新規細胞内氷晶形成測定法の開発と次世代三次元組織凍結保存 New
Grant-in-Aid for Scientific Research (C) 武藤誠 マウスモデルと臨床材料を用いた大腸がん幹細胞亜型の転移機構の解析  
Grant-in-Aid for Scientific Research (C) 中川靖章 心不全患者におけるTRPC3/C6シグナルのバイオマーカーとしての潜在的意義の検討  
Grant-in-Aid for Scientific Research (C) UEDA Shugo 大腸がんに対する新規分子標的治療薬FGFR3IIIc阻害薬の開発  
Grant-in-Aid for Scientific Research (C) 奥知慶久 大腸がんに対する新規分子標的治療薬FGFR3IIIc阻害薬の開発  
Grant-in-Aid for Scientific Research (C) 堀江昭史 卵丘細胞のメタボロームに着目したSLEの病態に即した胚培養系の開発  
Grant-in-Aid for Scientific Research (C) 堀江昭史 がん・生殖医療のためのヒト卵巣組織凍結法の最適化 New
Grant-in-Aid for Scientific Research (C) 堀江昭史 胚形態の動的解析と非侵襲的着床前胚異数性検査を併用した新規胚着床前診断手法の確立 New
Grant-in-Aid for Scientific Research (C) HONDA Noritsugu 呼吸筋トレーニングのアウトカムとしての呼吸筋量及び機能の評価方法の確立 New
Grant-in-Aid for Scientific Research (B) 中川靖章 心不全病態形成に関わる心筋エピゲノム制御回路の包括的解明と治療標的の同定  
Grant-in-Aid for Scientific Research (B) 川添准矢 マウス脂肪肝移植を用いた代謝免疫学的アプローチによる肝虚血再灌流障害の機序解明  
Grant-in-Aid for Scientific Research (B) 稲野将二郎 共有結合性人工アミノ酸を導入することによる生体タンパク質の超機能化 New
挑戦的研究(萌芽) 稲野将二郎 タンパク質分解系を利用した神経変性疾患の病態解明と治療法の探索  

厚生労働科学研究費補助金・厚生労働行政推進調査事業費補助金（分担）

研究種目 Co-researcher 研究課題名  
地域医療基盤開発推進研究事業 寺井美峰子 医療機関における国等が発信した医療安全にかかる情報の活用促進に向けた研究 New
難治性疾患政策研究事業 Tatsuo Tsukamoto 難病の克服に向けた研究推進と医療向上を図るための戦略的統括研究  
がん対策推進総合研究事業 堀江昭史 小児・AYA世代がん患者に対するがん・生殖医療における心理社会的支援体制の構築と安全な長期検体保管体制の構築を目指した研究―サバイバーシップ向上を志向して  

国立研究開発法人日本医療研究開発機構（AMED） （代表）

business Research and Development Representative R&D Project
創薬支援推進事業・創薬総合支援事業 稲野将二郎 神経変性疾患原因タンパク質の効率的な除去方法の探索

国立研究開発法人日本医療研究開発機構（AMED） （分担）

business Research and development contributor R&D Project
創薬ベンチャーエコシステム強化事業 石守崇好 MRIイメージングバイオマーカー開発とPⅠ試験後観察研究

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